If you use the Deadwood Distro you don't have to configure anything, Scalos is already assigned to the Extras/Scalos path.
The only Operations you have to do is to copy all the Scalos folders to the same locations in AROS (same folders)
Classes in SYS:Classes
Libs in SYS:Libs
Prefs in SYS:Prefs
System in SYS:System
Extras in SYS:Extras
With that done, go to the Extras/Scalos folder and run Scalos.
To Configure Scalos, you need to go to Extras/Scalos/Prefs and run the Preference Apps.
All this if Scalos is run from Wanderer, if you want to run Scalos directly, then something changes.